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Rakshit, K., Qian, J., Ernst, J

Diabetes 64(3):819827 Coskun T, Sloop KW, Loghin C, Alsina-Fernandez J, Urva S, Bokvist KB et al (2018) LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept

It does not quantify how much additional risk that adds

Medication Dose: Higher doses produce greater weight loss

Needle-Averse or Patients noncompliant with injection Patients who fear needles, travel frequently, or have difficulty making regular appointments for injections may prefer a self-administered oral option that maintains therapeutic efficacy

Some weight loss, even if modest and potentially temporary, provides health benefits