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For example, amino acids derived from lysosomal proteolysis are exported from the lysosome lumen to provide building blocks for protein synthesis while concomitantly promoting the activation of mTORC1

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To uncover whether Sirt3 participates in the IF-induced anti-inflammatory functions, we first analysed the protein levels of Sirt3 in microglia treated with IF and found the potential positive effects on regulating Sirt3 expression by IF