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These materials demonstrate high pH sensitivity, where acidic conditions trigger a surge in fluoride release, particularly pronounced in systems containing CaF 2 or fluorohydroxyapatite under cariogenic pH (4.5-5.5) generated by bacterial metabolism (Morawska-Wilk et al., 2025)

SPRS SPRS is an optical imaging technique that leverages the localized surface plasmon resonance (LSPR) effect of metal NPs

One compound, GliSODin, has been shown to promote bioactive SOD, CAT, and GPx levels via oral supplementation

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