GLP-1 plays a key role in glucose control, weight loss, digestion, and cardiovascular protection
Their pleiotropic effects, which range from anti-inflammatory, antioxidant, and metabolic regulation to neuroprotective and endothelial-stabilizing properties, are mediated through complex intracellular pathways, including the PI3K/Akt, AMPK, and NF-B signaling pathways
"This creates challenges related to desire and sexual attraction, potentially impacting overall sexual function." According to him, GLP-1s can also disrupt the balance of the estrogen hormone, noting that "this issue appears to be more pronounced in women using these peptides." He continued, "I have observed that many women experience significant side effects that lead them to discontinue the medication
Rise Ella McGovern for medical writing assistance and administrative support during the preparation of this manuscript
The steady inclusion of GLP-1s and SGLT2s has directed prescribing practices, away from the longstanding reliance on older, generic drugs
doi: 10.34067/KID.0005852020
