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The position-two winner will be the asset that delivers 20% at a price payers cover, a dose patients tolerate, and a compliance burden they accept

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Just before the declaration of COVID-19 as a pandemic, a Cochrane review of 48 controlled clinical trials, with 6299 patients treated with different drugs, including NAC, concluded that there was not enough evidence to establish with certainty whether corticosteroids, surfactants, NAC, statins and other drugs were effective in reducing mortality or the need/duration of mechanical ventilation in patients with ADRS [41]

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