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7.6 Anthraquinones: dual modulators of lipogenesis and antioxidant defense Anthraquinones alleviate ALD by suppressing the AMPK/SREBP-1c axis to inhibit de novo lipogenesis and activating the Nrf2/ARE pathway to upregulate antioxidant enzymes such as GST and GR (Cui et al., 2014

The mechanism of action is that it affects the production of NAD+ on an intracellular level (Neelakantan, 2019)

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