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We also summarize emerging biomarkers and ongoing clinical trials, and consider challenges such as inter-individual variability and the need to establish causal relationships

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NS4B is likely not engaged in the virus replication, but may contribute to the assembly and the release of the virus particles[69]

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Additionally, acatalasemia, a rare genetic anomaly characterized by impaired catalase activity (also recognized as Takahara disease), emerges due to aberrations in catalase function [31]