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For instance, intracellular signals of Rho-kinases, Rac, and Cdc42, which precipitate prothrombotic and anti-inflammatory activity of endothelial cells, are suppressed by statins (Figure 3) [59]

Liver histology Liver tissue was fixed overnight in 10% formaldehyde, transferred to 70% ethanol for 48 h and then processed into paraffin blocks

405 Cells were transiently transfected with CBS siRNA to probe the transcriptional regulation of sterol regulatory element binding protein (SREBP) (lipid transcription factor)

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