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This is an oncolytic virus therapy approved for advanced melanoma

And I can count on one hand the patients who [00:06:00] we had to discontinue or you know, it just wasn't right for them or they were having some side effects

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The concern stems from animal reproduction studies where these drugs affected normal fetal development pathways, though human pregnancy data remains limited because ethical guidelines prevent controlled trials in pregnant women

Bear in mind that topical and oral tretinoin vary in application and effects