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Retatrutide (compounded, investigational) As a triple agonist (GLP-1, GIP, glucagon), retatrutide is the most complex molecule of the three

Phentermine has its own safety profile: cardiovascular risk, dependency potential, and systemic stimulation that can worsen anxiety or sleep

Eduardo Grunvald, medical director for UC San Diego's Center for Advanced Weight Management

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According to the Summary of Product Characteristics (SmPC) approved by the MHRA, no dose adjustment is necessary for patients with mild, moderate, or severe renal impairment