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The multidisciplinary team, which comprised two mathematicians, a clinician and modeler, an epidemiologist, an immunologist, and a bioethicist, wanted to evaluate whether or not that finding was plausible

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The gene spans approximately 55.7 kb across 8 exons and codes for a protein in the NNMT/PNMT/TEMT family (EC 2.1.1.1)

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Both homocysteine and MMA levels can be elevated in renal insufficiency, hypovolaemia, and inherited metabolic defects.12 Although elevated homocysteine and MMA levels can aid in the diagnosis of vitamin B 12 deficiency in people with normal serum vitamin B 12 levels, there are concerns about these metabolite assays