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10.1038/sj.mp.4000849 161 Mouatt-PrigentA.MurielM.-P.GuW.-J.El HachimiK.LckingC.BriceA.et al (2004)

When SAM is reduced from MTHFR-impaired methionine regeneration, EZH2 and other histone methyltransferases lose substrate availability producing progressive loss of repressive histone methylation marks at senescence-promoting gene promoters

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55 According to another study, intravenous administration of selenium with zinc and manganese significantly reduced the time COPD patients spent on mechanical ventilation

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