doi: 10.1038/nature14344 100 WangWGreenMChoiJEGijnMKennedyPDJohnsonJKet al
Your liver sees almost everything that comes into your body, Alan says, making it an incredibly important organ
PLoS ONE 12:e184709 Kim HW, Yu AR, Lee JW, Yoon HS, Lee BS, Park HW, Lee SK, Lee YI, Whang J, Kim JS (2022) Aconitate decarboxylase 1 deficiency exacerbates mouse colitis induced by dextran sodium sulfate
Macan H, Uykimpang R, Alconcel M, et al
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We wish to emphasise, however, that the present study did not measure any direct marker of hepatic or systemic oxidative stresssuch as the GSH/GSSG ratio, malondialdehyde, F2-isoprostanes, or 8-hydroxy-2-deoxyguanosineand the observed clinical pattern is equally compatible with several non-redox explanations: differential reversibility of the underlying precipitating event between phenotypes, differential intensity of concurrent standard-of-care interventions in the sicker subgroup (infection control, alcohol abstinence, diuretic optimisation, nutritional support), and statistical regression toward the mean in patients with the highest baseline biochemical values
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