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The primary available study, Naessen et al

doi:10.1007/s12035-014-8697-6 Chikahisa S, Si H

These results surpassed established benchmarks of effectiveness, according to Beth Zerr, PharmD, an assistant clinical professor of pharmacy practice at the University of Arizona in Tuscon

Weight-based dosing considerations While the standard clinical trial protocols use fixed-dose titration schedules regardless of body weight, some researchers adjust their approach based on body composition

Xu P, Xin Y, Zhang Z, Zou X, Xue K, Zhang H, et al