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In later, larger studies, amitriptyline was used as active comparator to gabapentin, pregabalin, and duloxetine, and was shown to have similar effects in relieving DPN pain as these other drugs [57-59]
In some cases, symptoms are driven more by how the body responds to normal hormonal fluctuations than by abnormal hormone levels themselves.16 Because of this, supplements may be most useful for people dealing with recurring, pattern-based symptoms such as mood changes around the menstrual cycle, persistent fatigue, irregular periods, or hot flashes even when lab values fall within normal ranges
2020 Jun;173:57-61
Better sleep often creates a positive cycle that supports energy, exercise performance, mood, and recovery
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