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Do not resume at the same dose level that caused severe symptoms

Report on 5-years experience with dimethylbiguanide (metformin, glucophage) in diabetic therapy

Over time, this compounds into a meaningful metabolic protection against weight regain

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Selection criteria for the eta-analysis Inclusion criteria were studies (1) including healthy participants, (2) utilising 1 H-MRS to measure GSH levels in specified brain regions, (3) giving mean and SD for each group, (4) patients with depression only and not bipolar affective disorder in accordance with criteria specified in the Diagnostic and Statistical Manual for Mental Disorders (DSM) or the International Classification of Diseases (ICD-11), (5) information provided on sex of patients