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Modern liver-specific IGF-1 knockout studies have shown that local IGF-1 contributes substantially to tissue IGF1R activation, separate from the endocrine pool

And unlike most pharmaceuticals, they work with your body's existing biology rather than overriding it

Two people using identical protocols may have completely different results simply because one received genuine product while the other received degraded, contaminated, or counterfeit material

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Healthcare system inertia makes systematic changes difficult to implement and sustain