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In naturally aged mice and in doxorubicin-treated mice, FOXO4-DRI treatment significantly improved physical fitness, restored fur density, improved renal function, and improved liver function effects attributed to the selective elimination of accumulated senescent cells

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[16] In this group, baseline ALT may already be mildly elevated

Add EDC and DMAP (HOOC-SS-BBR:EDC:DMAP molar ratio = 1:1.5:1) to the anhydrous DMSO, followed by ASP

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